首页> 外文会议>World biomaterials congress >A Mixed-micellar siRNA Delivery System for Gene Specific Cancer Therapeutics by a Synthetic Lethal Interaction Between KRAS Cdk4

【24h】

A Mixed-micellar siRNA Delivery System for Gene Specific Cancer Therapeutics by a Synthetic Lethal Interaction Between KRAS Cdk4

机译：基因特异性癌症治疗剂的混合胶束siRNA递送系统通过KRAS＆CDK4之间的合成致死相互作用

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

MMP_(siCdk4) was able to reduce the expression of Cdk4 gene either in A549 or HL7702. Only in A549 cell line that express KRAS mutations, knockdown Cdk4 could reduce a senescence response. It's a gene specific cancer therapeutics.

机译：MMP_（SICDK4）能够在A549或HL7702中减少CDK4基因的表达。只有在表达KRA突变的A549细胞系中，敲低CDK4可以降低衰老反应。它是一种基因特异性癌症治疗剂。

著录项

来源
《World biomaterials congress》|2012年||共1页
会议地点
作者
Cheng-Qiong Mao; Meng-Hua Xiong; Jun Wang;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类 TB347;
关键词

相似文献

外文文献
中文文献
专利

1. Synthetic lethal therapy for KRAS mutant non-small-cell lung carcinoma with nanoparticle-mediated CDK4 siRNA delivery [J] . MaoC.-Q., XiongM.-H., LiuY., Molecular therapy: the journal of the American Society of Gene Therapy . 2014,第5期

机译：纳米粒子介导的CDK4 siRNA递送对KRAS突变型非小细胞肺癌的合成致死治疗
2. Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies [J] . Michael Steckel, Miriam Molina-Arcas, Britta Weigelt, Cell research. . 2012,第8期

机译：确定合成致死相互作用的KRAS致癌基因依赖性癌细胞揭示了新型治疗靶向策略
3. Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies [J] . Michael Steckel, Julian Downward, David C Hancock, 细胞研究（英文版） . 2012,第008期

机译：确定合成致死相互作用的KRAS致癌基因依赖性癌细胞揭示了新型治疗靶向策略
4. A Mixed-micellar siRNA Delivery System for Gene Specific Cancer Therapeutics by a Synthetic Lethal Interaction Between KRAS Cdk4 [C] . Cheng-Qiong Mao, Meng-Hua Xiong, Jun Wang World biomaterials congress . 2012

机译：KRAS与Cdk4之间的合成致死相互作用的混合胶束siRNA递送系统，用于基因特异性癌症治疗。
5. Evaluation of therapeutic effect of IKK epsilon siRNA on breast cancer cells and development of a peptide-based siRNA delivery system [D] . Qin, Bin 2012

机译：评估IKK epsilon siRNA对乳腺癌细胞的治疗效果以及基于肽的siRNA递送系统的开发
6. Synthetic Lethal Therapy for KRAS Mutant Non-small-cell Lung Carcinoma with Nanoparticle-mediated CDK4 siRNA Delivery [O] . Cheng-Qiong Mao, Meng-Hua Xiong, Yang Liu, 2014

机译：纳米粒子介导的CDK4 siRNA传递的KRAS突变非小细胞肺癌的合成致命治疗。
7. Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies [O] . Michael Steckel, Miriam Molina-Arcas, Britta Weigelt, 2012

机译：克拉癌基因依赖性癌细胞中合成致命相互作用的测定揭示了新的治疗靶向策略
8. Genomewide Screen for Synthetic Lethal Interactions with Mutant KRAS in Lung Cancer. [R] . Yin-Yuan, M. 2017

机译：全基因筛选与肺癌突变KRas合成致死性相互作用。

A Mixed-micellar siRNA Delivery System for Gene Specific Cancer Therapeutics by a Synthetic Lethal Interaction Between KRAS Cdk4

摘要

著录项

相似文献

相关主题

期刊订阅