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In vitro bioactivity of IGF-1 mimetic peptide on human mesenchymal stem cells: a therapeutic agent for avascular tissue regeneration

机译:IGF-1模拟肽对人间充质干细胞的体外生物活性:养血组织再生的治疗剂

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The findings of this research show the treatment of hMSC's with IGF-1-mimicking peptide can significantly increase cell proliferation while retaining their pluripotency. While further investigation is required to study the long term effects of this peptide on cell differentiation in tissue engineering constructs, these results pave the way towards the stimulation of cartilage regeneration by synthetic biochemical signalling.
机译:该研究的结果表明,HMSC的治疗方法与IGF-1模拟肽可以显着提高细胞增殖,同时保留多能性。虽然需要进一步调查来研究该肽对组织工程结构中细胞分化的长期效果,但这些结果通过合成生化信号传导刺激了软骨再生的方法。

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