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pH-Responsive Hybrid Polymeric Vesicles for Targeted Anticancer Drug Delivery

机译:pH响应杂化聚合物囊泡,用于靶向抗癌药物递送

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In this work, DOX-loaded hybrid vesicles equipped with folate residues show capable of undergoing pH-induced DOX release and effective cellular uptake as compared to folate-free DOX-loaded hybrid vesicles, thus effectively facilitating intracellular DOX delivery. Such multifunctional hybrid vesicles are promising candidates as a carrier system for anticancer drug delivery.
机译:在这项工作中,配备有叶酸残留物的Dox加载的混合囊泡,其能够进行PH诱导的Dox释放和有效的蜂窝摄取,而无叶酸的杂交囊泡,从而有效促进细胞内DOX递送。这种多功能杂交囊泡是作为抗癌药物递送的载体系统的承诺候选者。

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