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Ontology-driven development of a clinical research information system

机译:本体驱动的临床研究信息系统开发

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Clinicians at Nottingham University Hospitals NHS Trust have developed a clinical information model that enables detailed patient data to be gathered in clinics, stored in a patient record, linked with samples in a Biobank and then used to identify and select patient cohorts for research studies. The objective has been to enable the assembly of cohorts based on any plausible combination of clinical and laboratory features. The model is represented as an ontology, coded in OWL/XML and is itself built upon an ontology-based information architecture. The model can be used to generate the runtime configuration and operational data structures for a clinical information system, which has been implemented using an open source toolkit developed at City University, London.
机译:诺丁汉大学医院NHS Trust的临床医生开发了一种临床信息模型,该模型使详细的患者数据能够在诊所中收集,存储在患者记录中,并与Biobank中的样本相关联,然后用于识别和选择用于研究的患者队列。目的是能够根据临床和实验室特征的任何合理组合来组建队列。该模型被表示为以OWL / XML编码的本体,它本身是基于基于本体的信息体系结构构建的。该模型可用于生成临床信息系统的运行时配置和操作数据结构,已使用伦敦城市大学开发的开源工具包实现了该模型。

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