Monodisperse microparticle generation from aqueous solutions

摘要

We present a new approach for the generation of monodispersed droplets and tailor-made microparticles of complex liquids from a star-shaped nozzle that precisely defines the dispensed droplet sizes. From two aqueous polymer solutions: 30w% Polyvinylpyrrolidone (PVP) (viscosity η ≈ 105 mPas) and 40w% PVP (η ≈ 490 mPas) droplet volumes of 3.9 nl and 3.2 nl respectively were generated employing a star-shaped silicon nozzle with a diameter of 183 µm. From 1w% Mannitol (η ≈ 1 mPas) droplets (100 pl) and particles (22 µm) were generated from a 59 µm nozzle. These results show for the first time particle generation with the StarJet method that could be applicable for the generation of monodispersed powders for use in healthcare, food and home care products.