Spiral Coated Guglielmi Detachable Coils for Intracranial Aneurysms: Optimizing Mechanical Properties with Biological Activity

摘要

We have successfully developed a mechanical strong yet flexible bioactive coil. The thin aPLGA provides a beneficial pro-inflammatory environment with limited impedance to flexibility. The acidic polymer coated coil with preserved mechanical properties may be applied for potentially successful therapeutic treatment through acute inflammation induced wound healing.