Coherent Anti-Stokes Raman Scattering Microscopy for Sensing Molecular Orientations

摘要

We report a radially polarized coherent anti-Stokes Raman scattering (CARS) microscopy to facilitate longitudinally oriented molecules detection. We demonstrate that combining both the radially and linearly polarized excitation schemes, CARS microscopy can be a very powerful tool for identifying the 3-D orientations of molecules with high sensitivity and chemical specificity.