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Automatic Classification System for the Diagnosis of Alzheimer Disease Using Component-Based SVM Aggregations

机译:使用基于组件的SVM聚合诊断阿尔茨海默氏病的自动分类系统

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The early detection of subjects with probable Alzheimer Type Dementia (ATD) is crucial for effective appliance of treatment strategies. Functional brain imaging including SPECT (Single-Photon Emission Computed Tomography) and PET (Positron Emission Tomography) are commonly used to guide the clinician's diagnosis. Nowadays, no automatic tool has been developed to aid the experts to diagnose the ATD. Instead, conventional evaluation of these scans often relies on subjective, time consuming and prone to error steps. This paper shows a fully automatic computer-aided diagnosis (CAD) system for improving the accuracy in the early diagnosis of the ATD. The proposed approach is based on the majority voting cast by an ensemble of Support Vector Machine (SVM) classifiers, trained on a component-based feature extraction technique which searches the most discriminant regions over the brain volume.
机译:早期发现可能患有阿尔茨海默氏痴呆症(ATD)的受试者对于有效应用治疗策略至关重要。功能性脑成像包括SPECT(单光子发射计算机断层扫描)和PET(正电子发射断层扫描)通常用于指导临床医生的诊断。如今,尚未开发出可帮助专家诊断ATD的自动工具。相反,对这些扫描的常规评估通常依赖于主观,耗时且易于出错的步骤。本文展示了一种用于提高ATD早期诊断准确性的全自动计算机辅助诊断(CAD)系统。所提出的方法基于支持向量机(SVM)分类器组合的多数表决,该分类器接受了基于组件的特征提取技术的训练,该技术可搜索大脑体积上最有区别的区域。

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