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Protein Folding Classification by Committee SVM Array

机译:通过委员会SVM阵列进行蛋白质折叠分类

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Protein folding classification is a meaningful step to improve analysis of the whole structures. We have designed committee Support Vector Machines (committee SVMs) and their array (committee SVM array) for the prediction of the folding classes. Learning and test data are ammo acid sequences drawn from SCOP (Structure Classification Of Protein database). The classification category is compatible with the SCOP. SVMs and committee SVMs are designed in an one-versus-others style both for chemical data and sliding window patterns (spectrum kernels). This generates the committee SVM array. Classification performances are measured in view of the Receiver Operating Characteristic curves (ROC). Superiority of the committee SVM array to existing prediction methods is obtained through extensive experiments to compute the ROCs.
机译:蛋白质折叠分类是改善整个结构分析的有意义的一步。我们已经设计了委员会支持向量机(委员会SVM)及其数组(委员会SVM数组)来预测折叠类别。学习和测试数据是从SCOP(蛋白质结构分类数据库)提取的氨基酸序列。分类类别与SCOP兼容。 SVM和委员会SVM在化学数据和滑动窗口模式(频谱内核)方面都采用“一对多”的设计。这将生成委员会SVM阵列。分类性能是根据接收器工作特性曲线(ROC)进行测量的。委员会SVM阵列相对于现有预测方法的优越性是通过广泛的实验来计算ROC所获得的。

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