Antitumor activity of DACHPt-loaded polymeric micelles against a bioluminescent lung metastasis tumor model

机译：用于生物发光肺转移肿瘤模型的分频加载的聚合物胶束的抗肿瘤活性

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Polymeric micelles incorporating (1,2- diaminocyclohexane)-platinum(Ⅱ) (DACHPt) were evaluated against a lung metastatic tumor model. DACHPt-loaded micelles (DACHPt/m) showed high efficiency in controlling metastatic growth and considerably extended the life span of mice. These results suggest that DACHPt/m could be an outstanding drug delivery system for oxaliplatin to treat metastatic or regionally spreaded tumors.

机译：掺入（1,2-二氨基环己烷）-Platinum（Ⅱ）（分别）的聚合物胶束对肺转移瘤模型进行评估。加载的胶束（Dachtpt / m）显示了控制转移性生长的高效率，并且大大延长了小鼠的寿命。这些结果表明，Dachtp / M可以是用于奥沙利铂的优秀药物输送系统，以治疗转移性或区域蔓延的肿瘤。

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《Controlled Release Society Annual Meeting and Exposition》|2007年||共2页
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Horacio Cabral; Nobuhiro Noshiyama; Kazunori Kataoka;
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中图分类生物工程学（生物技术）;
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1. Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1 in a mouse model of non-small cell lung cancer. [J] . Nagano T, Yasunaga M, Goto K, International Journal of Cancer =: Journal International du Cancer . 2010,第11期

机译：在非小细胞肺癌小鼠模型中，含SN-38的聚合胶束NK012与S-1的协同抗肿瘤活性。
2. Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1 in a mouse model of non-small cell lung cancer. [J] . Nagano T, Yasunaga M, Goto K, International Journal of Cancer =: Journal International du Cancer . 2010,第11期

机译：在非小细胞肺癌小鼠模型中，含SN-38的聚合胶束NK012与S-1的协同抗肿瘤活性。
3. Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma. [J] . Lim DS, Kwak YS, Kim JH, Chemotherapy: International Journal of Experimental and Clinical Chemotherapy . 2003,第3期

机译：链霉菌的网状粗蛋白对肺转移模型B16F10黑色素瘤的抗肿瘤功效。通过抑制黑色素瘤的生长来抑制肺转移。
4. Antitumor activity of DACHPt-loaded polymeric micelles against a bioluminescent lung metastasis tumor model [C] . Horacio Cabral, Nobuhiro Noshiyama, Kazunori Kataoka Controlled Release Society Annual Meeting and Exposition . 2007

机译：负载DACHPt的聚合物胶束对生物发光肺转移肿瘤模型的抗肿瘤活性
5. Structure--activity relationship studies of hybrid antitumor agents for the treatment of non-small cell lung cancer. [D] . Ma, Zhidong. 2009

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Antitumor activity of DACHPt-loaded polymeric micelles against a bioluminescent lung metastasis tumor model

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