RNA-containing antitumor agents, methods for activating immune cells, methods for suppressing metastasis of tumor cells, immunostimulators, agents for enhancing the antitumor effect of antitumor agents, and pharmaceutical compositions.

摘要

PROBLEM TO BE SOLVED: To provide an antitumor agent containing RNA that activates immune cells as an active ingredient. An antitumor agent containing at least one RNA selected from the group consisting of the following (i), (ii) and (iii). (i) RNA having the base sequence represented by SEQ ID NO: 3 or SEQ ID NO: 6 (ii) RNA having a base sequence having 90% or more identity with the base sequence represented by SEQ ID NO: 3 or SEQ ID NO: 6 and capable of increasing the antitumor activity of cells. (iii) RNA that has a part of the base sequence of (i) or (ii) above and can increase the antitumor activity of cells. [Selection diagram] FIG. 7