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Evaluation of In-Vitro Release Properties of Vancomycin Microspheres Prepared with Polyaspartic Acid

机译:用聚天冬氨酸制备的万古霉素微球的体外释放性能评价

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The biodegradable polyaminoacid microspheres containing vancomycin hydrochloride (VANCO) were prepared by the solvent evaporation method with different polymer:drug ratios (1:1, 2:1, 3:1 and 4:1). The encapsulation efficiency and the in vitro release characteristics of the drug-loaded microspheres were studied. Results show that the microsphere formulations have shown sustained-release effect.
机译:通过具有不同聚合物的溶剂蒸发方法制备含有万古霉素(Vanco)的可生物降解的聚氨基酸微球:药物比(1:1,2:1,3:1和4:1)。研究了药物负载的微球的封装效率和体外释放特性。结果表明,微球配方表明持续释放效果。

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