The effects of particle surface properties and storage condition on powder flow properties

摘要

Good powder flow properties are needed for solid handling including mixing,pneumatic conveying, wet granulation, tabletting and so on. In order to obtain thedesired bulk flow properties, a good selection of processing and storage conditions isrequired. In the past, much attention has been given to relate bulk flow with powderproperties such as particle size distribution, bulk and tap density, and shape andmorphology. However, very little has been done to study the influence of interparticleinteractions on bulk flow.It is the aim of this paper to investigate the link between inter-particle interactions andflow properties of powder being stored under different conditions and prepareddifferently. Crystalline adipic acid before and after ball milling will be stored underdifferent humidity conditions. AFM will be used to study the friction-load dependenceat single particle level while Jenike shear tester will be used to measure the bulk yieldloci. The results will provide useful guideline into the selection of particle preparationmethod as well as storage condition to achieve the desired powder flow properties.