Ultrasonic Contrast Perfusion Imaging Approach Based on RF Echo Decorrelation

摘要

Existing ultrasonic contrast microbubble specific imaging methods are all Doppler-related multi-pulse techniques. A single-pulse microbubble destruction based echo decorrelation (DCR) imaging approach to perfusion detection is proposed and discussed in this paper. To evaluate this method, two experiments were performed using a commercial B-mode ultrasonic system with radiofrequency (RF) output on two in vitro phantoms. An ultra-high speed acquisition interface was employed for the acquisition of raw RF data. The data were processed off-line with different decorrelation algorithms. An optimal algorithm was chosen for perfusion image construction on a blow mimic and capillary flow phantom, respectively. The results of one-dimension (1-D) DCR process and two-dimension (2-D) imaging construction shows that the proposed method is valid in bubble based perfusion detection.