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RISK ASSESSMENT OF AIRBORNE ALLERGENS - AN EXAMPLE OF THE EXPOSURE ASSESSMENT PROTOCOL FOR LABORATORY ANIMAL ALLERGENS

机译:空气致敏原的风险评估-实验室动物致敏原的暴露评估协议的示例

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Risk assessment of allergen exposure is difficult because the relationship between exposure concentration,sensitisation, and symptoms has not been fully established. Laboratory animal allergens belong to important occupational health risk factors; 10-32 % of those working with laboratory animals develop allergic diseases. This paper introduces a comprehensive assessment protocol established for the evaluation of the risk due to exposure to laboratory animal allergens. The protocol includes questionnaires to the management and employees, hazard identification (i.e., observation and measurements in the workplace), and a summary of generally recommended methods to reduce allergen exposure. Based on these, the synopsis on the critical points needing implementation of effective control measures is then presented. The protocol encompasses several elements applicable to risk assessment of allergens generally, and, therefore, it can be applied wider in risk assessment than merely for laboratory animal allergens.
机译:由于尚未充分确定暴露浓度,致敏性和症状之间的关系,因此难以对过敏原暴露进行风险评估。实验动物过敏原属于重要的职业健康危险因素;与实验动物打交道的人中有10-32%会患过敏性疾病。本文介绍了建立的综合评估方案,用于评估由于暴露于实验动物过敏原而引起的风险。该方案包括给管理人员和雇员的问卷,危害识别(即在工作场所的观察和测量)以及一般推荐的减少过敏原暴露方法的摘要。在此基础上,提出了需要采取有效控制措施的关键点的提要。该协议涵盖了适用于一般过敏原风险评估的几个要素,因此,它不仅可以用于实验室动物过敏原,而且可以在风险评估中更广泛地应用。

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