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THE INFLUENCE OF FILLERS ON TABLETING AND DRUG RELEASE FROM HPMC MATRICES

机译:填料对HPMC基质压片和药物释放的影响

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摘要

The influence of compression force on tableting and drug release from hydroxypropylmethylcellulose (HPMC) matrices, formulated with three commonly used fillers have been investigated. Compression force affected drug release profiles when insoluble or partially soluble filler was used.
机译:研究了压制力对由三种常用填料配制的羟丙基甲基纤维素(HPMC)基质的压片和药物释放的影响。当使用不溶或部分可溶的填充剂时,压缩力会影响药物释放曲线。

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