THE EFEECT OF CRYSTALLINE MICROSTRUCTURE ON THE DRUG RELEASE BEHAVIOR OF POLY(ε-CAPROLACTONE) MICROSPHERES

机译：晶体的微观结构对聚（ε-己内酯）微球药物释放行为的影响

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The release behavior of papaverine from poly(ε-caprolactone) (PCL) microparticles with different crystalline microstructures was investigated in the phosphate buffer solution. The results suggest that the microstructure of PCL microparticles such as size and crystalline morphology plays an important role in the drug release behavior.

机译：在磷酸盐缓冲溶液中研究了罂粟碱从具有不同晶体微观结构的聚（ε-己内酯）（PCL）微粒中的释放行为。结果表明，PCL微粒的微观结构（例如大小和晶体形态）在药物释放行为中起重要作用。

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《Proceedings of the 29th Annual Meeting of the Controlled Release Society》|2002年|p.570-571|共2页
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Kilwon Cho; Jong Cheol Jeong; Jae Young Lee;
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正文语种
中图分类化学工业;
关键词
biodegradable polymer; poly(ε-caprolactone); diffusion controlled release; crystalline microstructure;

机译：可生物降解的聚合物;聚ε-己内酯;扩散控制释放;晶体微观结构;

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专利

1. Effects of crystalline microstructure on drug release behavior of poly(epsilon-caprolactone) microspheres [J] . Jeong JC., Lee J., Cho K. Journal of Controlled Release: Official Journal of the Controlled Release Society . 2003,第3期

机译：晶体微观结构对聚ε-己内酯微球释药行为的影响
2. Preparation, characterization, and drug release behaviors of drug nimodipine-loaded poly(epsilon-caprolactone)-poly(ethylene oxide)-poly(epsilon-caprolactone) amphiphilic triblock copolymer micelles. [J] . Ge H, Hu Y, Jiang X, Journal of pharmaceutical sciences. . 2002,第6期

机译：载有尼莫地平的聚（ε-己内酯）-聚（环氧乙烷）-聚（ε-己内酯）两亲性三嵌段共聚物胶束的制备，表征和释药行为。
3. Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide)/poly(epsilon-caprolactone) (PCL) amphiphilic block copolymeric nanospheres - II. Thermo-responsive drug release behaviors [J] . Kim SY., Lee YM., Ha JC. Journal of Controlled Release: Official Journal of the Controlled Release Society . 2000,第3期

机译：聚（环氧乙烷）-聚（环氧丙烷）-聚（环氧乙烷）/聚（ε-己内酯）（PCL）两亲嵌段共聚物纳米球-II。热响应药物释放行为
4. THE EFEECT OF CRYSTALLINE MICROSTRUCTURE ON THE DRUG RELEASE BEHAVIOR OF POLY(ε-CAPROLACTONE) MICROSPHERES [C] . Kilwon Cho, Jong Cheol Jeong, Jae Young Lee Annual meeting of the Controlled Release Society . 2002

机译：结晶微观结构对聚（ε-己内酮）微球的药物释放行为的效应
5. Experimental and computational investigations of therapeutic drug release from biodegradable poly(lactide-co-glycolide) (PLG) microspheres. [D] . Berchane, Nader Samir. 2007

机译：从可生物降解的聚（丙交酯-共-乙交酯）（PLG）微球释放治疗性药物的实验和计算研究。
6. In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer [O] . Chang Yang Gong, Shuai Shi, Peng Wei Dong, 2009

机译：基于Pluronic f127和聚（乙二醇）-聚（ε-己内酯）-聚（乙二醇）共聚物的新型热敏复合水凝胶的体外药物释放行为
7. drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer [O] . 2009

机译：基于Pluronic f127和聚（乙二醇）-聚（ε-己内酯）-聚（乙二醇）共聚物的新型热敏复合水凝胶的药物释放行为

THE EFEECT OF CRYSTALLINE MICROSTRUCTURE ON THE DRUG RELEASE BEHAVIOR OF POLY(ε-CAPROLACTONE) MICROSPHERES

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