- - Reductive Degradable Poly-caprolactone Polymer Having Covalent Bond Between Diselenodipropionate and Poly-caprolactone Polymer Anticancer Composition and Drug Delivery Composition Comprising the Same

摘要

The present invention relates to a reductive degradable poly (epsilon-caprolactone) [diselenide poly (ε-caprolactone), PSe_2] polymer having diselenide bonding and having poly (epsilon-caprolactone) covalent-bonded to both ends of diselenodipropionate, and an anti-cancer composition or a drug delivery composition using the polymer. According to the present invention, a synthesized PSe_2 polymer can form nanoparticles through self-assembly in water, thereby being usefully applied as a carrier capable of carrying various drugs including anti-cancer agents into cells or an anti-cancer composition.