Luminescent Porous Silicon Nanoparticles as Drug Carrier

摘要

In this work, the applicability of luminescent porous silicon (PS) nanoparticles as ascorbic acid (AA) carrier has been studied. PS nanoparticles have been realized reducing in multi-sized particles porous silicon free-standing film placed in deionized water by sonication and filtering through 0.45 um membrane. The PS nanoparticles are water-soluble and highly fluorescent. PS nanoparticles are loaded by AA, monitoring the fluorescence spectra by a spectrofluorimeter. Before assessing the loading of AA into PS nanoparticles dispersed in water, the emission stability of PS solution has been acquired. Once stabilized the signal and loaded the AA, the presence and the real absorption of AA onto PS nanoparticles has been evaluated from emission quenching of the silicon nanoparticles.