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Enhancement of bone bonding strengths of titanium alloys by alkali and heat treatments

机译:通过碱和热处理增强钛合金的骨结合强度

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The purpose of this study is to investigate whether alkali-and heat-treated titanium alloys can bond to bone. Surface-smoothed rectangular plates of Ti6Al4V, Ti6Al2Nb1Ta, and Ti15Mo5Zr3Al were prepared. The alkali-and heat-treated and untreated each alloy implants were implanted into proximal tibiae of mature rabbits, treated implant for right side and untreated for left. At 8 and 16 weeks after operation detaching test and histological examination were performed. Untreated implants showed almost no bonding even at the 16 weeks after implantation. In contrast treated implants showed bonding to bone both at 8 and 16 weeks. Histological examination showed that alkali-and heat-treated alloys bonded to bone directly. On the other hand untreated implants had intervening fibrous tissue between bone and plate. Although in this study even tentative conditions of treatments enhance bonding strength of titanium alloys, the most suitable conditions of treatments for highest bonding strength should be determined by further experiments. These new bioactive titanium alloys are supposed to be available for weight-bearing and bone-onding orthopaedic devices.
机译:这项研究的目的是研究经碱和热处理的钛合金是否可以与骨骼结合。制备了表面光滑的Ti6Al4V,Ti6Al2Nb1Ta和Ti15Mo5Zr3Al矩形板。将经过碱处理,热处理和未处理的每种合金植入物植入成熟兔的胫骨近端,右侧植入处理的植入物,左侧植入未处理的植入物。术后第8周和第16周进行脱离试验和组织学检查。未经处理的植入物甚至在植入后16周也几乎没有粘结。相比之下,经过治疗的植入物在8周和16周时均显示出与骨骼的粘合。组织学检查表明,经碱和热处理的合金直接与骨骼结合。另一方面,未经处理的植入物在骨和板之间有介入的纤维组织。尽管在本研究中,即使试验性的处理条件也能增强钛合金的结合强度,但应通过进一步的实验确定最合适的处理条件,以实现最高的结合强度。这些新的生物活性钛合金被认为可用于承重和支撑骨的矫形设备。

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