Individual-based simulation of the clustering behaviour of epidermal growth factor receptors.

摘要

This paper describes ongoing work on a project to simulate the behaviour of epidermal growth factor receptors. These are structures which can be found on the surface of cells in the body, which receive and process chemical signals concerned with cell growth. We describe the implementation of a program which simulates the stimulation and clustering behaviour of these structures, discuss how we scale up this simulation so that we can simulate a whole cell on a tractable timescale, and discuss ongoing work in which we are calibrating our simulation against results from experiments.