Polymer microfluidic devices are gaining in popularity for bio-applications. In both commonly used methods for the fabrication of polymer microfluidic devices, i.e. injection molding and hot-embossing, the quality of mold insert is of high importance. Micro Powder Injection Molding (uPlM) provides a suitable option for metal mold insert fabrication. In this paper, two mold inserts with micro-features of different patterns and sizes were produced using 316L stainless steel powder and in-house binder system. The mold inserts were successfully used to produce Cyclic Olefin Copolymer (COC, trade name TOPAS) micromixer plates with micro-channels of 100 urn width and 50 um width. Compared with micro-machined hot work steel mold inserts, the quality of the micro-channels is better as far as surface roughness and dimensional tolerance is concerned.
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