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Effect of Varying Phantom Size in Dosimetry of Iridium-192: A Comparison of Experimental Data with EGSnrc Monte Carlo Calculation

机译:幻像尺寸的变化对铱192剂量学的影响:实验数据与EGSnrc蒙特卡罗计算的比较

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There have been increasing numbers of studies in high dose-rate (HDR) brachytherapy dosimetry, which have shown that the phantom size has significant effect on the dose delivered. The most frequently used methodology consisted of verifying the Monte Carlo calculations with the experimental measurements. This paper primarily reports the effects of varying scatter material thickness above an Iridium-192 (~(l92)Ir) HDR source by using a PTW Roos chamber (PTW, Germany) and the EGSnrc Monte Carlo code (National Research Council Canada, Canada). Virtual Water (Med-Cal, USA) was utilized as a scatter material. A microSelectron remote afterloader unit (Nucletron, Netherlands) was utilized to deliver ~(l92)lr source. The Roos chamber placed in the recess of a 20 mm thick Virtual Water slab was positioned above the backscatter material. A catheter attached to the treatment tube from the remote afterloader unit was fixed above the central axis of a Roos chamber. Secondly, the position dependence of a Roos chamber with respect to the source has been investigated. This was achieved by placing two different thick scatter materials between the planes of the source and a Roos chamber. The results from both experimental measurements and Monte Carlo calculations has shown increased dose with increasing scatter material thickness above ~(192)Ir source, with Monte Carlo calculated results showing less variation in dose. The dose output reduced considerably with increasing thickness of scatter materials between the chamber and the source.
机译:高剂量率(HDR)近距离放射治疗剂量学研究越来越多,这些研究表明幻影大小对所输送的剂量具有显着影响。最常用的方法包括用实验测量值验证蒙特卡洛计算。本文主要通过使用PTW Roos腔室(德国PTW)和EGSnrc蒙特卡罗代码(加拿大国家研究委员会,加拿大)在Iridium-192(〜(192)Ir)HDR源上方改变散射材料厚度的影响进行了报道。 。虚拟水(美国Med-Cal)被用作分散材料。使用MicroSelectron远程后装载器装置(荷兰Nucletron)来输送〜(192)lr离子源。放置在20毫米厚虚拟水板凹槽中的Roos腔室位于反向散射材料上方。从远程后装载器单元连接到处理管的导管固定在Roos腔室的中心轴上方。其次,已经研究了Roos腔室相对于源的位置依赖性。这是通过在源和Roos腔的平面之间放置两种不同的厚散射材料来实现的。实验测量和蒙特卡洛计算的结果均显示,随着〜(192)Ir源以上散射材料厚度的增加,剂量也随之增加,而蒙特卡洛计算的结果表明剂量变化较小。随着腔室和源之间的散射材料厚度的增加,剂量输出显着降低。

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