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Application of 2 Step IMRT to Spinal Tumors: A Preliminary Retrospective Planning Study Comparison with Classical IMRT

机译:2步IMRT在脊柱肿瘤中的应用:与经典IMRT的初步回顾性规划研究比较

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A geometry based treatment methodology, 2 Step IMRT, was employed to perform a retrospective planning study for spinal tumors. Four such tumor localisations were considered: 3 cases with a single treatment volume and one case with two nested treatment volumes. Four simple metrics were defined and used to evaluate the quality of the plans. The results show that 2 Step IMRT performs at least as well as a reference plan, simultaneously maintaining or improving the dose coverage of the PTV(s), the dose gradient near the dominant organ at risk (spinal column) and reducing the number of segments required for treatment delivery. Currently the generation of 2 Step segments is labor intensive. However, this will be automated in the near-future to enable a more comprehensive study to be performed.
机译:采用基于几何学的治疗方法,即两步IMRT,对脊柱肿瘤进行回顾性计划研究。考虑了四个这样的肿瘤定位:3例具有单一治疗量的病例和1例具有两个嵌套治疗量的病例。定义了四个简单的指标,并用于评估计划的质量。结果显示2步IMRT至少执行和参考计划一样的工作,同时保持或改善PTV的剂量覆盖率,处于危险中的主要器官附近的剂量梯度(脊柱)并减少段数需要提供治疗。当前,两步细分的产生是劳动密集型的。但是,这将在不久的将来实现自动化,以进行更全面的研究。

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