In-vitro studies of femtosecond transscleral photodisruption

摘要

Transcleral photodisruption may provide a noninvasive method for creating partial thickness scleral channels to reduce elevated intraocular pressure associated with glaucoma. We achieved subsurface photodisruption in vitro without damaging overlying tissues with three techniques: (1) use of long laser wavelengths, (2) application of pressure, and (3) application of a dehydrating agent. Using 1 and 3, we were able to photodisrupt the internal surface of a full thickness block of sclera by focusing through the tissue.