INSTRUMENTAL NEUTRON ACTIVATION ANALYSIS OF RIB BONE SAMPLES AND BONE REFERENCE MATERIALS

摘要

In the last years has been an increasing interest in the determination of trace elements in biological tissues in order to elucidate their roles in human beings as well as to diagnose diseases. Also, trace element determinations in bones have been carried out because essential and toxic elements are deposited in bones.rnThe purpose of this work was to establish the methodology of instrumental neutron activation method (INAA) to analyse bone tissues and provide results of trace element in rib bones. In order to evaluate the precision and the accuracy of the results, the reference materials NIST SRM 1400 Bone Ash and MST SRM 1486 Bone Meal were analysed. Human rib bone samples were obtained from accident victims' autopsies performed at the Institute of Forensic Medicine of the Universidade Mogi das Cruzes, SP. The samples were wrapped in polyethylene foils and stored in a freezer until they were analysed. The ribs were dissected and cleaned free from connected soft tissues (marrow and periosteum) and then washed with distilled water. The small pieces of cortical bones were lyophilized for analyses.