CORRELATIONS OF PBDES IN HOUSE DUST AT DIFFERENT SAMPLING TIMES AND ASSOCIATION OF BDE-47 IN HOUSE DUST AND HUMAN PLACENTAL TISSUE

摘要

The indoor environment is one of the major human exposure sources for polybrominated diphenyl ethers (PBDEs). Several studies have shown the importance of dust as a source of exposure, however, many different sampling techniques have been applied. The variability in dust sampling is not well studied, thus in the current study a second round of dust sampling was performed three months after a previous sampling, both based on domestic vacuum cleaner bags. The dust samples were dominated by BDE-209 (54.48-95380 ng/ dw), which made up 84% of the total PBDE on average. Principal component analysis grouped the congeners according to the technical PBDE mixtures. The preliminary comparison of the two dust samplings showed good correlations, especially for BDE-47 and -99, indicating that a single sample is representative for the general contamination level. Furthermore, a statistically significant correlation was observed for BDE-47 in house dust and placental tissue of residents after planned caesarean section (p = 0.048, r=0.29). Further analyses are in progress.