Pressure effects on lyotropic lipid mesophases and model membrane system-effects on the structure, phase behaviour and kinetics of phase transformations

摘要

Amphiphilic lipid molecules, which provide valuable model systems for lyotropic mesophases and iomembranes, display a variety of polymorphic phases, depending on their molecular structure and environmental conditions, such as the water content, pH, inonic strength, temperature and pressure [1-5]. The basic structural element of biological membranes consists of a lamellar phospholipid ilayer matrix. Due to the large hydrophobic effect, most phospholipid bilayers associate in water already at very low concentrations (<10~(-12) mol.L~(-1)).