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Nanoengineered biomaterials to fight gastric infection: exploring the glycan-adhesin specific interaction

机译：纳米工程生物材料可抗击胃部感染：探索聚糖-粘附素特异性相互作用

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H. pylori adhesion to Leb-Mic is ligand specific, and efficiency studies revealed their increased capacity to compete with mice and human gastric mucosa for H. pylori adhesion comparing to chitosan microspheres without glycans. These results highlight the potential of glycan nanoengineered chitosan microspheres as alternative or complementary treatment to H. pylori gastric infection.

机译：幽门螺杆菌对Leb-Mic的粘附是配体特异性的，效率研究表明，与不含聚糖的壳聚糖微球相比，幽门螺杆菌与小鼠和人胃粘膜竞争幽门螺杆菌的能力增强。这些结果突出了聚糖纳米工程化的壳聚糖微球作为幽门螺杆菌胃感染的替代或补充治疗的潜力。

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《European conference on biomaterials》|2014年|360-360|共1页
会议地点 Liverpool(GB)
作者
Ines C. Goncalves; Ana M. S. Costa; A. Magalhaes; Celso A. Reis; M. Cristina L. Martins;
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INEB - Instituto de Engenharia Biomedica da Universidade do Porto Portugal FEUP - Faculdade de Engenharia da Universidade do Porto Portugal IPATIMUP - Instituto de Patologia e Imunologia Molecular da Universidade do Porto Portugal both authors contributed equally to this work;

INEB - Instituto de Engenharia Biomedica da Universidade do Porto Portugal FEUP - Faculdade de Engenharia da Universidade do Porto Portugal both authors contributed equally to this work;

IPATIMUP - Instituto de Patologia e Imunologia Molecular da Universidade do Porto Portugal;

INEB - Instituto de Engenharia Biomedica da Universidade do Porto Portugal;

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2. Micro- and Nanoengineering Approaches to Control Stem Cell-Biomaterial Interactions [J] . Ali Khademhosseini, Alireza Dolatshahi-Pirouz, Kristian Kolind, Journal of Functional Biomaterials . 2011,第3期

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4. Nanoengineered biomaterials to fight gastric infection: exploring the glycan-adhesin specific interaction [C] . Ines C. Goncalves, Ana M. S. Costa, A. Magalhaes, European Conference on Biomaterials . 2014

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5. Biomaterial design for specific cellular interactions: Role of surface functionalization and geometric features. [D] . Kolhar, Poornima. 2012

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6. Non-Invasive Luciferase Imaging of Type I Interferon Induction in a Transgenic Mouse Model of Biomaterial Associated Bacterial Infections: Microbial Specificity and Inter-Bacterial Species Interactions [O] . Muhammad Imran Rahim, Andreas Winkel, Stefan Lienenklaus, 2020

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7. Non-Invasive Luciferase Imaging of Type I Interferon Induction in a Transgenic Mouse Model of Biomaterial Associated Bacterial Infections: Microbial Specificity and Inter-Bacterial Species Interactions [O] . Muhammad Imran Rahim, Andreas Winkel, Stefan Lienenklaus, 2020

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Nanoengineered biomaterials to fight gastric infection: exploring the glycan-adhesin specific interaction

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