Nanoengineered biomaterials to fight gastric infection: exploring the glycan-adhesin specific interaction

摘要

H. pylori adhesion to Leb-Mic is ligand specific, and efficiency studies revealed their increased capacity to compete with mice and human gastric mucosa for H. pylori adhesion comparing to chitosan microspheres without glycans. These results highlight the potential of glycan nanoengineered chitosan microspheres as alternative or complementary treatment to H. pylori gastric infection.