Numerical evaluation of the slope and intercept of end-systolic pressure-volume relation

摘要

Numerical evaluation of two methods to calculate slope and intercept of end-systolic pressure-volume relation (ESPVR) in the left ventricle is presented. The mathematical formalism is based on results previously published in which the active force of the myocardium (also called isovolumic pressure P_(iso)) is introduced in the formalism describing the pressure-volume relation (PVR) in the left ventricle. The numerical calculation is simple and can be easily implemented in routine clinical work, only the ventricular pressure P_m near end-systole needs to be estimated. A thick-walled cylindrical model contracting symmetrically is assumed for the left ventricle.