Poly(Ethylene Glycol) Hydrogels as Possible Multidrug Resistance Associated Protein (MRP) Inhibitors

机译：聚乙二醇水凝胶可能是多药耐药相关蛋白（MRP）抑制剂

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

Multidrug resistance (MDR) has been recognized by the scientific community as one of the major hurdles in the bioavailability of broad spectrum of drugs. This work focuses on the examination of the effects of the variables involved in hydrogel design on t

机译：多药耐药性（MDR）已被科学界确认为广泛药物生物利用度的主要障碍之一。这项工作的重点是检查水凝胶设计中涉及的变量对t的影响。

著录项

来源
《Engineering in Medicine and Biology Society, 2007 Annual International Conference of the IEEE》|2007年|P.5111-5114|共4页
会议地点 Lyon,France
作者
Torres-Lugo; M.; Santos-Roman; N.; Mendez; J.; Licha; M.;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类
关键词
biochemistry; biomedical materials; cellular transport; drug delivery systems; molecular biophysics; polymer gels; proteins; radiation therapy; sodium compounds; Caco-2 cell monolayer transport; Fickian effect; chemotherapeutic agent 5-Fluoracil; controlled drug del;

机译：生物化学生物医学材料；细胞运输；药物输送系统；分子生物物理学聚合物凝胶；蛋白质放射治疗;钠化合物Caco-2细胞单层运输；菲克效应化疗药物5-氟尿嘧啶;药物管制;

相似文献

外文文献
中文文献
专利

1. Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2). [J] . Flanagan SD, Cummins CL, Susanto M, Pharmacology: International Journal of Experimental and Clinical Pharmacology . 2002,第3期

机译：比较过表达多药耐药蛋白（P-糖蛋白）和多药耐药相关蛋白（MRP1和MRP2）的细胞系中呋塞米和长春碱的分泌。
2. Flavonoid dimers as bivalent modulators for P-glycoprotein-based multidrug resistance: Synthetic apigenin homodimers linked with defined-length poly(ethylene glycol) spacers increase drug retention and enhance chemosensitivity in resistant cancer cel [J] . Chan KF, Zhao YZ, Burkett BA, Journal of Medicinal Chemistry . 2006,第23期

机译：类黄酮二聚体可作为基于P糖蛋白的多药耐药性的二价调节剂：合成芹菜素同型二聚体与定长的聚（乙二醇）间隔基连接可增加药物保留并增强耐药性细胞的化学敏感性
3. Thermogelling hydrogels of poly(epsilon-caprolactone-CO-D,L-lactide)-poly(ethylene glycol)-poly(epsilon-caprolactone-CO-D,L-lactide) and poly(epsilon-caprolactone-CO-L-lactide)poly(ethylene glycol)-poly(epsilon-caprolactone-CO-L-lactide) aqueous solu [J] . Jiang ZQ, Deng XM, Hao JY Journal of Polymer Science, Part A. Polymer Chemistry . 2007,第17期

机译：聚（ε-己内酯-CO-D，L-丙交酯）-聚（乙二醇）-聚（ε-己内酯-CO-D，L-丙交酯）和聚（ε-己内酯-CO-L-丙交酯）的热凝胶水凝胶聚乙二醇-聚ε-己内酯-CO-L-丙交酯水溶液
4. Poly(Ethylene Glycol) Hydrogels as Possible Multidrug Resistance Associated Protein (MRP) Inhibitors [C] . Torres-Lugo M., Santos-Roman N., Mendez J., Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2007

机译：聚（乙二醇）水凝胶作为多药耐药相关蛋白（MRP）抑制剂
5. Development of Photopatterned Macroporous Poly(ethylene glycol) Hydrogels within Microfluidic Channels to Quantify Protein Tyrosine Kinase Activity [D] . Lee, Andrew Ghin-Lig 2011

机译：在微流控通道内光图案化的大孔聚乙二醇水凝胶的发展，以量化蛋白质酪氨酸激酶活性。
6. In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer [O] . Chang Yang Gong, Shuai Shi, Peng Wei Dong, 2009

机译：基于Pluronic f127和聚（乙二醇）-聚（ε-己内酯）-聚（乙二醇）共聚物的新型热敏复合水凝胶的体外药物释放行为
7. drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer [O] . 2009

机译：基于Pluronic f127和聚（乙二醇）-聚（ε-己内酯）-聚（乙二醇）共聚物的新型热敏复合水凝胶的药物释放行为

Poly(Ethylene Glycol) Hydrogels as Possible Multidrug Resistance Associated Protein (MRP) Inhibitors

摘要

著录项

相似文献

相关主题

期刊订阅