Using Bonded Silica Solid Phase Microextraction Fibers as a Screening Tool for Pharmaceuticals and Personal Care Products in Drinking Water

摘要

EPA method 1694 is used in the determination of pharmaceuticals and personal care products (PPCPs) in environmental samples. These PPCPs have received considerable press attention in recent years, with growing concerns over the presence of these compounds in the world's drinking waters. This method uses solid phase extraction (SPE) and high performance liquid chromatography combined with tandem mass spectrometry (LC-MS/MS) to quantitate 50 PPCPs in a variety of environmental matrices. The existing sample extraction process is tedious and time consuming with typical processing times of 60-90 minutes per sample. A faster, more efficient extraction procedure is desired. Using Solid Phase Microextraction (SPME), a comparision of both methods is described. Advantages and disadvantages of each method are reported including sample detection and recovery.