In-vivo Performance of a Time-delayed Tablet Formulation in Man, using Gamma Scintigraphy

机译：使用Gamma闪烁扫描技术在人体内的延时片剂的体内性能

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A press-coated tablet formulation based onrncontrolled erosion of a wax-disintegrant layerrnwas investigated in in-vitro and in-vivo studiesrnIn-vivo release from the core tablet wasrndetermined by gamma scintigraphy and in-vitrornand in-vivo lag-times compared. Erosion of therncoating layer appeared slower in-vivo than invitro.

机译：在体外和体内研究中研究了基于蜡-崩解剂层的受控侵蚀的压制片剂制剂，通过γ闪烁显像法确定了从核心片剂中的体内释放，并比较了玻璃体内和体内滞后时间。体内涂层的侵蚀似乎比体内的要慢。

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《Controlled Release Society 31st annual meeting transactions: abstracts》|2004年|1-2|共2页
会议地点 Honolulu HI(US)
作者
D. Leaokittikul; B. Lindsay; B.OMahony; Stanley A; H.N.E. Stevens;
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作者单位

Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow G4 0NR, Scotland, UK;

Bio-Images Research, Glasgow Royal Infirmary, G4 0SF, Scotland, UK;

Bio-Images Research, Glasgow Royal Infirmary, G4 0SF, Scotland, UK;

Bio-Images Research, Glasgow Royal Infirmary, G4 0SF, Scotland, UK;

Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow G4 0NR, Scotland, UKrnBio-Images Research, Glasgow Royal Infirmary, G4 0SF, Scotland, UK h.n.e.stevens@strath.ac.uk;

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In-vivo Performance of a Time-delayed Tablet Formulation in Man, using Gamma Scintigraphy

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