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Directed Evolution of an Artificial Cell Lineage

机译:人工细胞谱系的定向进化

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摘要

Biological development is a complex process that mediates between genotypes, to which mutations occur, and phenotypes, on which selection acts. Properties of development can therefore have considerable impact on evolution. However, in many existing simulation models of development, the developmental process itself is difficult to recover and/or analyse. We have previously introduced a model of development in which the developmental process is represented as a cell lineage. Here we use this model to further explore the control of development, and the influence that development has on shaping an adaptive landscape.
机译:生物发育是一个复杂的过程,介导发生突变的基因型和选择作用的表型之间。因此,发展的性质会对发展产生重大影响。但是,在许多现有的开发仿真模型中,开发过程本身很难恢复和/或分析。我们之前已经介绍了一种发展模型,其中的发展过程以细胞谱系表示。在这里,我们使用这个模型来进一步探索对开发的控制,以及开发对塑造适应性景观的影响。

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