Synthesis and Characterization of Polysulfobetaines and their Random Copolymers

摘要

[3-(Methacryloylamino)propyl)dimethyl(3-sulfopropyl)ammonium hydroxide] polymer, known as poly(MPDSAH), and the random copolymers based on methyl methacrylate (MMA), methacryloxyethyltrimethylammonium (METAC) and 3-sulfopropyl methacrylate potassium (SPMA) were synthesized via Reversible Addition-Fragmentation Chain Transfer (RAFT) polymerization technique. Solution properties of these (co)polymers in response to temperature and ionic strength have been studied using dynamic light scattering (DLS). For poly(MPDSAH), polymer size decreased from 500 nm to 10 nm (in diameter) when the polymer aqueous solution was heated up from 15℃ to 60℃ or added 20 mM sodium chloride. The solution behaviour of poly(METAC-stat-MMA-stat-SPMA) is opposite to that of poly(MPDSAH): the size of polymer increased from 10 nm to 20 nm (in diameter) depending upon the elevating temperature or the addition of salt.