Knowledge Extraction and Extrapolation Using Ancient and Modern Biomedical Literature

机译：利用古代和现代生物医学文献进行知识提取和外推

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Extraction of knowledge from biomedical literature is one of the major problems for researchers. This primarily involves identification of novel associations between biological objects (genes, proteins, diseases, medicines etc.). These associations are commonly extracted by mining biomedical resources such as the PUBMED which contains a large volume of information. An automated approach towards this end will reduce a substantial amount of time for biomedical researchers. In this paper we discuss a methodology to extract such associations and to assign a significance measure to the generated hypotheses. The computed significance value for the extracted knowledge can be considered as association strength between biological objects. The generated hypotheses with large significance can be considered for further experimental validation by biologists. In this paper we conduct two different validation studies of the results, which provide justification for the approach that was followed to generate the hypotheses.

机译：从生物医学文献中提取知识是研究人员的主要问题之一。这主要涉及鉴定生物学对象（基因，蛋白质，疾病，药物等）之间的新型关联。通常通过挖掘生物医学资源（例如包含大量信息的PUBMED）来提取这些关联。为此目的的自动化方法将减少生物医学研究人员的大量时间。在本文中，我们讨论了一种提取此类关联并为所产生的假设分配显着性度量的方法。所提取的知识的计算出的显着性值可以视为生物对象之间的关联强度。生物学家可以考虑所产生的具有重大意义的假设，以进行进一步的实验验证。在本文中，我们对结果进行了两次不同的验证研究，这些研究为产生假设所采用的方法提供了依据。

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《Advanced Information Networking and Applications Workshops, 2009. WAINA '09》|2009年|996-1001|共6页
会议地点 Bradford(GB);Bradford(GB)
作者
Vaka H.G.G.; Mukhopadhyay S.;
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Dept. of Comput. Inf. Sci., Indiana Univ., Indianapolis, IN;

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data mining; knowledge acquisition; medical administrative data processing; PUBMED; association strength; biomedical literature; biomedical resources mining; knowledge extraction; knowledge extrapolation; Association Extraction; Ayurveda; Text Mining; Transitive Closure;

机译：数据挖掘;知识获取;医疗行政数据处理; PUBMED;关联强度;生物医学文献;生物医学资源挖掘;知识提取;知识外推;联想提取;阿育吠陀;文本挖掘;传递闭包;

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机译：现代文学证实了古代印度关于牲畜繁殖和营养的文献
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机译：现代文学证实了古代印度关于动物住房和健康的文献
4. Knowledge Extraction and Extrapolation Using Ancient and Modern Biomedical Literature [C] . Harsha Gopal Goud Vaka, Snehasis Mukhopadhyay International Conference on Advanced Information Networking and Applications . 2009

机译：古代近现代生物医学文学的知识提取与推断
5. Mining novel knowledge from biomedical literature using statistical measures and domain knowledge [D] . Jha, Kishlay. 2016

机译：使用统计方法和领域知识从生物医学文献中挖掘新颖知识
6. Comparing a knowledge-driven approach to a supervised machine learning approach in large-scale extraction of drug-side effect relationships from free-text biomedical literature [O] . Rong Xu, QuanQiu Wang 2015

机译：从大规模文本医学生物医学文献中大规模提取药物副作用关系时将知识驱动方法与有监督的机器学习方法进行比较
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Knowledge Extraction and Extrapolation Using Ancient and Modern Biomedical Literature

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