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Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging

机译:具有变形镜的新型自适应透镜的比较及其在高分辨率体内OCT成像中的应用

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摘要

We present a novel adaptive lens that can correct high order aberrations, and which has the potential to increase the diffusion of adaptive optics to many new applications by simplifying the integration of a wavefront corrector inside existing systems. The adaptive lens design that we present can correct for Zernike wavefront aberrations up to the 4th order. The adaptive lens performance are compared with the one of a membrane and bimorph deformable mirrors used together in a wide field microscope setup, using a Shack-Hartmann wavefront sensor for closed loop control. The adaptive lens was also integrated with Fourier Domain Optical Coherence Tomography for in-vivo imaging of mouse retinal structures using an image based wavefront sensorless control.
机译:我们提出了一种新型的自适应透镜,该透镜可以校正高阶像差,并且可以通过简化现有系统中波前校正器的集成来增加自适应光学器件向许多新应用的扩散。我们提出的自适应透镜设计可以校正Zernike波前像差至4阶。使用Shack-Hartmann波前传感器进行闭环控制,将自适应透镜的性能与在广角显微镜设置中一起使用的膜和双压电晶片可变形镜之一进行比较。自适应透镜还与傅里叶域光学相干断层扫描技术集成在一起,以使用基于图像的波前无传感器控制对小鼠视网膜结构进行体内成像。

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  • 来源
  • 会议地点 San Francisco CA(US)
  • 作者单位

    CNR-Institute for Photonics and Nanotechnology, Via Trasea 7, 35131, Padova, Italy;

    CNR-Institute for Photonics and Nanotechnology, Via Trasea 7, 35131, Padova, Italy,Hilase project, Institute of Physics AS CR v.v.i., Na Slovance 2, 18221, Prague, Czech Republic;

    School of Engineering Science, Simon Fraser University, Burnaby, BC, V5A1S6, Canada;

    UC Davis RISE Small Animal Ocular Imaging Facility, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, CA 95616;

    UC Davis RISE Small Animal Ocular Imaging Facility, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, CA 95616;

    UC Davis RISE Small Animal Ocular Imaging Facility, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, CA 95616;

    CNR-IBCN, Via E. Ramarini, 32 - 00015 Monterotondo Scalo Roma;

    UC Davis RISE Small Animal Ocular Imaging Facility, Department of Cell Biology and Human Anatomy, University of California Davis, Davis, CA 95616,Vision Science and Advanced Retinal Imaging laboratory (VSRI), Department of Ophthalmology Vision Science, University of California Davis, Sacramento, CA 95817;

    School of Engineering Science, Simon Fraser University, Burnaby, BC, V5A1S6, Canada;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Adaptive Optics; Optical Coherence Tomogrphy; In-vivo maging;

    机译:自适应光学光学相干断层扫描;体内成像;

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