Relationship between Segmental Duplications and Repeat Sequences in Human Chromosome 7

摘要

A various types of repeat sequences are abundant in genomic sequence, and are associated with the biological phenomena at distinct levels. In particular, comparative analyses of whole-genome-sized sequence data reveal that the periodic sequences causes the segmental duplication that is a type of chromosomal structural arrangement In this study, we analyze the relationships between die large-scale segmental duplication of chromosome and die periodic sequences. For this purpose, the periodic sequences are detected by two repeat detection tools, TRF and STEPSTONE, to detect repeats of genomic sequence, and the distribution of detected periodic sequences is corresponded with the locations on the chromosome where the segmental duplications are observed.