MOBILITY OF IMMUNE LIGANDS SIGNAL MOLECULES IN THE MODEL PLANT ARABIDOPSIS

摘要

Pathogen associated molecular patterns (PAMPs) are conserved structures recognized by the innate immune system, which elicit an immediate immune response in both plants and animals. Bacterial pathogens can release several different PAMPs for which there are plant receptors on the cell surface. After a local bacterial infection, plants can confer immunity against a subsequent infection to leaves distal from the point of infection. This indicates that there are mobile molecules that mediate systemic responses. PAMPs can be potent elicitors of local plant innate immunity that can induce systemic acquired resistance (SAR) in distal leaves. We are interested in understanding when and where the bacterial- and plant-derived molecules and signals that affect local and systemic immunity act. Therefore, we have used a powerful set of Arabidopsis plant mutants altered in PAMP receptors or SAR components together with fluorescent and/or radiolabeled PAMP or a plant SAR signal to study their movement. We will present our findings about the movement of PAMPs and plant signals and the genetic requirements for their movement. We will present a model showing our functional insights about signaling mechanisms. This work is funded by the Department of Energy and the National Science Foundation.