Secondary Structures of (Poly)peptides within Constrained Polymeric Architectures

摘要

Ordered secondary structures of peptides in nature,such as α-helices and β-sheets,play crucial role in forming organized tertiary structures of proteins,which dominate their functions and properties as well as their biological activities.The stabilization of these secondary conformations will not only guarantee the proper activities of the proteins but also prevent them from forming abnormal amyloid fiber aggregates.