Design, simulation and characterization of microfluidic system for human immunodeficiency virus detection

摘要

Development of a specialized fluidic microsystem for HIV diagnosis from the reaction dependent of the affinity antigen-antibody. Based on knowledge about virus detection in laboratory, we pretend to decrease time spent to obtain results. In a first phase, this device will have a filtering zone, provided of small canals, causing that only specific cells could reach the next phase of membrane destruction for virus extraction; finally, specialized chemical sensors will react with these compounds, and it will show a colored signal to indicate diagnosis.