New Activated Carbon Drugs

摘要

New water-soluble cellulose derivative (WSCD) of polyelectrolyte nature has been suggested for preparing quicklyrndisintegrated drug forms of activated carbon and also combined drugs containing both aspirin, antacid, antibiotics etc. andrncarbon. The results of sedimentation analysis, studies of aggregative stability and rheological properties of suspensions ofrnfibrous activated carbon in the presence of new and well-known water-soluble polymers have been reviewed. It has beenrnfound that suspensions stabilized by WSCD display the lowest degree of structuring, the highest stability, narrower particlernsize distribution, and greater amount of particles incapable of gravity sedimentation. Such physicochemical suspensionrncharacteristics in combination with high specific surface and sorption activity allow obtaining drugs with increasedrnbioavailability, reducing the therapeutic dose and treatment period.