Analysis of peptide composition and structure of cytochrome P-450nor2

摘要

Cytochrome P-450 has mono-oxygenase activities, and catalyzes mono-oxygenation reaction. It also plays important roles in detoxication and synthesis of steriod hormone [1-2]. Recently, it was found that a unique cytochrome P-450 was involved in fungal denitrification, acting as a nitric oxide reductase (named P-450nor) [3]. There are 3 kinds of cytochrome P-450nor. One is from Fusarium oxysporum, i.e. C. P-450nor1 and C.P450nor2. We successfully cloned and sequenced C.P-450nor2 cDNA. The peptide sequence deduced from the cDNA was analysed by using GENETYX software.