Enhanced expression of protein phosphatase 2A associated with hyper-phosphorylation of histone H1 in Alzheimer's disease brain.

Mori S; Cao Y; Sogawa K; Kondo K; Sakai T; Hino N; Yamashiro H; Okada M; Miyamoto K; Kawaguchi Y; Mashiba T; Norimatsu H

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Enhanced expression of protein phosphatase 2A associated with hyper-phosphorylation of histone H1 in Alzheimer's disease brain.

机译：蛋白磷酸酶2A的表达增强与阿尔茨海默氏病脑中组蛋白H1的过度磷酸化有关。

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In this study, we analyzed high expression of protein phosphatase (PP) 2A in Alzheimer's disease brain compared to that of the control brain, which result from hyperphosphorylation of histone H1. PP1alpha and PP1gamma1 were slightly expressed in all cases, but there was no relation to the levels of the phosphate in histone H1.

机译：在这项研究中，我们分析了阿尔茨海默氏病脑中蛋白质磷酸酶（PP）2A与对照组相比的高表达，这是由于组蛋白H1的过度磷酸化导致的。 PP1alpha和PP1gamma1在所有情况下均略有表达，但与组蛋白H1中的磷酸盐含量无关。

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《Research communications in molecular pathology and pharmacology》 |2003年第0期|共7页
作者
Mori S; Cao Y; Sogawa K; Kondo K; Sakai T; Hino N; Yamashiro H; Okada M; Miyamoto K; Kawaguchi Y; Mashiba T; Norimatsu H;
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正文语种 eng
中图分类基础医学;
关键词
Alzheimer Disease; Histones; Phosphoprotein Phosphatase; Phosphotransferases; 组蛋白类; 磷蛋白磷酸酶; 磷酸转移酶类;

机译：Alzheimer Disease;Histones;Phosphoprotein Phosphatase;Phosphotransferases;组蛋白类;磷蛋白磷酸酶;磷酸转移酶类;

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1. Enhanced expression of protein phosphatase 2A associated with hyper-phosphorylation of histone H1 in Alzheimer's disease brain. [J] . Mori S, Cao Y, Sogawa K, Research communications in molecular pathology and pharmacology . 2003,第0期

机译：蛋白磷酸酶2A的表达增强与阿尔茨海默氏病脑中组蛋白H1的过度磷酸化有关。
2. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. [J] . Sontag E, Luangpirom A, Hladik C, Journal of Neuropathology and Experimental Neurology: Official Journal of the American Association of Neuropathologists, Inc . 2004,第4期

机译：蛋白质磷酸酶2A ABalphaC酶表达水平的改变与阿尔茨海默氏病病理相关。
3. Downregulation of protein phosphatase 2A by apolipoprotein E: Implications for Alzheimer's disease [J] . Veena Theendakara, Dale E. Bredesen, Rammohan V. Rao Molecular and cellular neurosciences . 2017,第期

机译：脂蛋白蛋白磷酸酶2A的下调e：对阿尔茨海默病的影响
4. Protein Interaction Partners of Protein Phosphatase 2A Catalytic Subunit in Rat β-Islet cells Using Quantitative Mass Spectrometry [C] . Divyasri Damacharla, Khadija Syeda, Xiangmin Zhang, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：使用定量质谱法在大鼠β-胰岛细胞中蛋白质磷酸酶2A催化亚基的蛋白质相互作用伴侣
5. Oxidatively-modified proteins: I. Proteomic identification of specifically-oxidized proteins in Alzheimer's disease brain. II. Modulation of synaptosomal membrane lipid bilayer asymmetry by 4-hydroxy-2-trans-nonenal. [D] . Castegna, Alessandra. 2003

机译：氧化修饰的蛋白质：I.阿尔茨海默氏病脑中特定氧化蛋白质的蛋白质组学鉴定。二。突触体膜脂质双层不对称的4-羟基-2-反式壬醛的调节。
6. Enhanced expression of an exocrine pancreatic protein in Alzheimers disease and the developing human brain. [O] . S M de la Monte, M Ozturk, J R Wands 1990

机译：外分泌胰腺蛋白在阿尔茨海默氏病和人类大脑发育过程中的增强表达。
7. Altered Expression Levels of the Protein Phosphatase 2A ABαC Enzyme Are Associated with Alzheimer Disease Pathology [O] . Estelle Sontag, Ampa Luangpirom, Christa Hladik, 2004

机译：蛋白质磷酸酶2aabαc酶的改变表达水平与阿尔茨海默病病理相关
8. Phosphorylation of the Butyrate-Enhanced Protein, Histone H1 exp 0 , in Chinese Hamster Cells [R] . D'Anna, J. A., Gurley, L. R., Becker, R. R., 1980

机译：中国仓鼠细胞中丁酸盐增强蛋白，组蛋白H1 exp 0的磷酸化

Enhanced expression of protein phosphatase 2A associated with hyper-phosphorylation of histone H1 in Alzheimer's disease brain.

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