Protein Interaction Partners of Protein Phosphatase 2A Catalytic Subunit in Rat β-Islet cells Using Quantitative Mass Spectrometry

摘要

Largest PP2A interaction network till date in rat β-islet cells Validation of the identified partners will give insight into the regulation of PP2A. Further validation of glucose responsive partners will help understand role of PP2A under high glucose conditions. Significant complexes may be targeted later to alter the composition and thereby prevent the demise of the β-islet cells under glucotoxic conditions.