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COMPOSITIONS COMPRISING A METAL SOURCE, DITHIOCARBAMATE AND CYCLODEXTRIN
COMPOSITIONS COMPRISING A METAL SOURCE, DITHIOCARBAMATE AND CYCLODEXTRIN
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机译:作品由一个金属源,硫代氨基甲酸和环糊精
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摘要
The present invention provides combinations and pharmaceutical compositions comprising a dithiocarbamate such as disulfiram and cyclodextrin, with a source of a heavy metal. Surprisingly, we found a synergistic potentiation of the anti-tumor effect, when a dithiocarbamate/heavy metal mixture was combined with a cyclodextrin. The combination of the invention is particularly useful in the treatment of tumor diseases, and other disorders. Provided are the combination, pharmaceutical compositions and kits, as well as methods for the preparation of the combinations of the invention.
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