A single nucleotide polymorphism marker composition for diagnosing an adverse reactions with angiotensin converting enzyme inhibitor and a method using the same

摘要

A composition and kit for diagnosing angiotensin converting enzyme inhibitor adverse reactions comprising a single nucleotide polymorphism (SNP) marker, and a method of providing information on the risk of angiotensin converting enzyme inhibitor adverse reactions using the marker. Using a composition for diagnosing angiotensin convertase inhibitor adverse reactions comprising at least one gene single nucleotide polymorphism (SNP) marker selected from the group consisting of NELL1, ABO, PDE11A, CACNA1D and SLCO1B1 according to an aspect Because high-risk groups can be effectively diagnosed or classified, ACEI can be effectively used without adverse reactions to reduce the risk of patients with cardiovascular disease and to provide personalized treatment.