The present invention relates to a method for recombinant production of a fusion protein comprising multiple malaria antigens for inducing immune responses comprising a combination of antibodies. In particular, the fusion proteins of the present invention comprise fragments of both Pfs230 and Pfs48/45 to lower the required threshold of functional antibodies and to reduce the risk of escape mutations. Thus, the fusion proteins of the present invention are suitable for use in a multivalent malaria vaccine.
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