PROGNOSTIC METHOD FOR AGGRESSIVE LUNG ADENOCARCINOMAS

摘要

The present invention relates to methods based on miRNA biomarkers for the prognosis of aggressive lung adenocarcinoma (ADC) including early-stage (stage I) disease, preferably in fresh-frozen or in formalin-fixed, paraffin-embedded (FFPE) specimens. More in particular, the invention refers to the use of 7-miRNA, 14-miRNA or 19-miRNA prognostic signatures in a method for prognostic risk stratification of ADC, preferably for identify patients with aggressive early-stage lung adenocarcinoma (namely C1-ADC).